Quetiapina (Aggiornato al 23/01/2017)

A cura di Simona Lucchesi. UOSD Farmacologia Clinica. AOU “G. Martino” Messina

Principio attivo

Effetto

Aprepitant (1)

Aumento delle concentrazioni sieriche di quetiapina

Warfarin (2-4)

Rischio di sanguinamento e aumento dell’INR


Bibliografia

  1. Verwimp-Hoeks MP. Aprepitant quetiapine: a clinically significant drug interaction in a patient treated for head and neck cancer. Ann Oncol Mar 2012; 23: 801-802.
  2. Rogers T, et al. Possible interaction between warfarin and quetiapine (letter). J Clin Psychopharmacol 1999; 19: 382-383.
  3. Product Information: COUMADIN(R) oral tablets, intravenous injection powder lyophilized for solution, warfarin sodium oral tablets, intravenous injection powder lyophilized for solution. Bristol-Myers Squibb Company (per FDA), Princeton, NJ, Oct, 2011.
  4. Yang FW, Liang CS. Multiple intracerebral hemorrhages in an elderly patient after adding quetiapine to a stable warfarin regimen. Gen Hosp Psychiatry 2011; 33: 302.

Link

Ultimo aggiornamento: 08 febbraio 2017